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Introduction of Novel Drug Delivery Systems

Introduction of Novel Drug Delivery Systems PDF Author: Sonal Vyas
Publisher: CBS Publishers & Distributors Pvt Limited, India
ISBN: 9789388527811
Category :
Languages : en
Pages :
Book Description
This is a useful textbook and resource for undergraduateand postgraduate students and anyone in the working concepts of a drug delivery system and its performance. A novel drug delivery system refers to strategy, technology, formulation-based approaches and customized system(s) developed for safe administration and within body transportation of drugs as needed for optimum therapeutic benefits while ensuring minimum to nil toxic effects. Multidisciplinary approaches and cutting edge technology have been used to develop the carrier modules to deliver the contained drug to the target tissues in a preprogrammed manner. The process desirably modifies the drug distribution and accumulation, thereby producing optimum therapeutic effects. Carrier-mediated drug delivery has emerged as a powerful technology for the treatment of various difficult pathologies. The therapeutic index of conventional and novel drug is enhanced owing to specificity due to targeting of drug to the particular tissue. This book includes an introduction to novel drug delivery, oral osmotic pumps, bioadhesive and mucoadhesive systems, multiple emulsions, colon-specific drug delivery systems, transdermal drug delivery systems, spherical crystallization, microemulsion, implants and inserts, micellar systems, liposomes, microspheres and microcapsules, nanoparticles, resealed erythrocytes, transfersomes and ethosomes, organogels, dendrimers, niosomes, solid lipid nanoparticles, drug conjugates, cyclodextrin complexes, multifunctional nanomedicines, and floating drug delivery system(s). Each chapter attempts to discuss introduction, concept, progress, status and future prospects of the concerned novel drug delivery system.

Introduction of Novel Drug Delivery Systems

Introduction of Novel Drug Delivery Systems PDF Author: Sonal Vyas
Publisher: CBS Publishers & Distributors Pvt Limited, India
ISBN: 9789388527811
Category :
Languages : en
Pages :
Book Description
This is a useful textbook and resource for undergraduateand postgraduate students and anyone in the working concepts of a drug delivery system and its performance. A novel drug delivery system refers to strategy, technology, formulation-based approaches and customized system(s) developed for safe administration and within body transportation of drugs as needed for optimum therapeutic benefits while ensuring minimum to nil toxic effects. Multidisciplinary approaches and cutting edge technology have been used to develop the carrier modules to deliver the contained drug to the target tissues in a preprogrammed manner. The process desirably modifies the drug distribution and accumulation, thereby producing optimum therapeutic effects. Carrier-mediated drug delivery has emerged as a powerful technology for the treatment of various difficult pathologies. The therapeutic index of conventional and novel drug is enhanced owing to specificity due to targeting of drug to the particular tissue. This book includes an introduction to novel drug delivery, oral osmotic pumps, bioadhesive and mucoadhesive systems, multiple emulsions, colon-specific drug delivery systems, transdermal drug delivery systems, spherical crystallization, microemulsion, implants and inserts, micellar systems, liposomes, microspheres and microcapsules, nanoparticles, resealed erythrocytes, transfersomes and ethosomes, organogels, dendrimers, niosomes, solid lipid nanoparticles, drug conjugates, cyclodextrin complexes, multifunctional nanomedicines, and floating drug delivery system(s). Each chapter attempts to discuss introduction, concept, progress, status and future prospects of the concerned novel drug delivery system.

Novel Drug Delivery Systems for Phytoconstituents

Novel Drug Delivery Systems for Phytoconstituents PDF Author: Madhu Gupta
Publisher: CRC Press
ISBN: 1351057626
Category : Health & Fitness
Languages : en
Pages : 336
Book Description
Novel Drug Delivery Systems for Phytoconstituents discusses general principles of drug targeting, construction material and technological concerns of different phytoconstituent in delivery systems. It focuses on the development of novel herbal formulations and summarizes their method of preparation, type of active ingredients, route of administration, biological activity and their applications. It dicusses therapeutic activities of plant derived chemicals, their limitations in clinical applications and novel drug delivery solutions to overcome them to provide better therapeutic effects with controlled and targeted drug delivery. Focus on drug delivery of phytomolecules Act as bridge between natural product scientist and clinical doctors Discusses mechanism of poor bioavailability of herbal molecules Increases awareness towards phytochemical efficacy Summarizes efficient novel delivery systems-based formulations. It extensively covers the applications of novel drug delivery systems including polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid capsules, liposomes, phytosomes, microsphere, transferosomes, and ethosomes. Some chapters are especially focused on anticancer phytodrugs, silymarin, andrographolide, berberine, and curcumin delivery with special emphasis on their application.

Advanced Drug Delivery

Advanced Drug Delivery PDF Author: Ashim Mitra
Publisher: John Wiley & Sons
ISBN: 1118662849
Category : Medical
Languages : en
Pages : 530
Book Description
Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to datewith the state of the science, presenting the basics, formulationstrategies, and therapeutic applications of advanced drug delivery.The book demonstrates how core concepts of pharmaceutical sciences,chemistry, and molecular biology can be combined and applied inorder to spark novel ideas to design and develop advanced drugdelivery systems for the treatment of a broad range of humandiseases. Advanced Drug Delivery features contributions from aninternational team of pharmaceutical scientists. Chapters reflect athorough review and analysis of the literature as well as theauthors' firsthand experience developing drug delivery systems. Thebook is divided into four parts: Part I, Introduction and Basics of Advanced DrugDelivery, explores physiological barriers, stability,transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offerstested and proven strategies for advanced delivery of both smallmolecules and macromolecules Part III, Translational Research of Advanced DrugDelivery, focuses on regulatory considerations andtranslational applications of advanced drug delivery systems forthe treatment of cardiovascular diseases, cancer, sexuallytransmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery inEmerging Research Areas, examines stem cell research,cell-based therapeutics, tissue engineering, and molecularimaging Each chapter provides objectives and assessment questions tohelp readers grasp key concepts and assess their knowledge as theyprogress through the book. Advanced Drug Delivery is recommended for graduates andupper-level undergraduates in the pharmaceutical sciences who needa solid foundation in the basics. It is also recommended forpharmaceutical professionals who want to take advantage of new andemerging applications in advanced drug delivery systems.

Novel Drug Delivery Systems for Chinese Medicines

Novel Drug Delivery Systems for Chinese Medicines PDF Author: Nianping Feng
Publisher: Springer Nature
ISBN: 9811634440
Category : Medical
Languages : en
Pages : 336
Book Description
This book describes the essential and cutting-edge concepts based on the frontier of pharmaceutical research in TCM, underlying scientific principles, and current advancements of drug delivery systems for Chinese medicines, including sustained-release drug delivery systems, trans-nasal drug delivery systems, dermal and transdermal drug delivery systems, etc. Novel carriers and emerging technologies (such as 3D printing) are also covered. The book provides readers with an overall picture of drug delivery systems for Chinese medicines and also yields benefits for the pharmaceutical industry with regard to TCM-based drug development.

Drug Delivery and Targeting

Drug Delivery and Targeting PDF Author: Anya M. Hillery
Publisher: CRC Press
ISBN: 0203302761
Category : Medical
Languages : en
Pages : 448
Book Description
The advances in biotechnology and molecular biology over recent years have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of disease. However, such potential is severely compromised by significant obstacles to delivery of these drugs in vivo. These obstacles are often so great that effective drug delivery and targeting is now recognized as the key to effective development of many therapeutics. Advanced drug delivery and targeting can offer significant advantages to conventional drugs, such as increased efficiency, convenience, and the potential for line extensions and market expansion. An accessible and easy-to-read textbook, Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists is the first book to provide a comprehensive introduction to the principles of advanced drug delivery and targeting, their current applications and potential future developments, including: *Methods to optimize therapeutic efficacy, and the related commercial implications *Difficulties with drug absorption, unwanted distribution and premature inactivation / elimination *Attempts to minimize toxicity or alter immunogenicity *Methods to achieve rate-controlled drug release and effective drug targeting *Novel and established routes of delivery *Use of new generation technologies such as biosensors, microchips, stimuli-sensitive hydrogels and plasmid-based gene therapy This volume is indispensable for pharmaceutical students, scientists and researchers.

Novel Drug Delivery Systems and Regulatory Affairs

Novel Drug Delivery Systems and Regulatory Affairs PDF Author: B. K. Nanjwade
Publisher: CBS Publishers & Distributors Pvt Limited, India
ISBN: 9789388527453
Category : Medical
Languages : en
Pages :
Book Description
Targeted towards undergraduate and postgraduate students, the purpose of this textbook is to introduce pharmacy students to the basic systems of pharmaceutical principles and technologies applied in the preparation of various novel drug delivery systems. It also provides an in-depth introduction to the regulatory agencies and Current Good Manufacturing Practices (CGMP). This book caters to anyone who is interested in the subject or working in the industry, clinicians and research scholars. It is written in simple, lucid style with easily-understandable language so that it is useful for self study. The illustrations and tables provide a clear understanding of the concepts.

Drug Delivery Applications of Noninvasive Imaging

Drug Delivery Applications of Noninvasive Imaging PDF Author: Chun Li
Publisher: John Wiley & Sons
ISBN: 1118356837
Category : Medical
Languages : en
Pages : 478
Book Description
Cost-effective strategies for designing novel drug deliverysystems that target a broad range of disease conditions In vivo imaging has become an important tool for thedevelopment of new drug delivery systems, shedding new light on thepharmacokinetics, biodistribution, bioavailability, localconcentration, and clearance of drug substances for the treatmentof human disease, most notably cancer. Written by a team ofinternational experts, this book examines the use of quantitativeimaging techniques in designing and evaluating novel drug deliverysystems and applications. Drug Delivery Applications of Noninvasive Imaging offersa full arsenal of tested and proven methods, practices andguidance, enabling readers to overcome the many challenges increating successful new drug delivery systems. The book begins withan introduction to molecular imaging. Next, it covers: In vivo imaging techniques and quantitativeanalysis Imaging drugs and drug carriers at the site of action,including low-molecular weight radiopharmaceuticals, peptides andproteins, siRNA, cells, and nanoparticles Applications of imaging techniques in administration routesother than intravenous injection, such as pulmonary and oraldelivery Translational research leading to clinical applications Imaging drug delivery in large animal models Clinical applications of imaging techniques to guide drugdevelopment and drug delivery Chapters are based on a thorough review of the currentliterature as well as the authors' firsthand experience workingwith imaging techniques for the development of novel drug deliverysystems. Presenting state-of-the-technology applications of imaging inpreclinical and clinical evaluation of drug delivery systems,Drug Delivery Applications of Noninvasive Imaging offerscost-effective strategies to pharmaceutical researchers andstudents for developing drug delivery systems that accuratelytarget a broad range of disease conditions.

Novel Drug Delivery Systems and Regulatory Affairs

Novel Drug Delivery Systems and Regulatory Affairs PDF Author: Sudhakar Yajaman & Jayaveera K.N.
Publisher: S. Chand Publishing
ISBN: 8121942578
Category : Medical
Languages : en
Pages :
Book Description
Novel Drug Delivery Systems | Transdermal Drug Delivery Systems | Mucoadhesive Drug Delivery Systems | Targeted Drugdelivery Systems | Regulatory Agencies | Quality Assurance | Good Manufacturing Practices | Validation

Nanopharmaceutical Advanced Delivery Systems

Nanopharmaceutical Advanced Delivery Systems PDF Author: Vivek Dave
Publisher: Wiley-Scrivener
ISBN: 9781119711667
Category : Computers
Languages : en
Pages : 512
Book Description
The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

Recent Advances in Novel Drug Carrier Systems

Recent Advances in Novel Drug Carrier Systems PDF Author: Ali Demir Sezer
Publisher: BoD – Books on Demand
ISBN: 9535108107
Category : Medical
Languages : en
Pages : 516
Book Description
This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.